Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 5/20 | 0.42 |
| ▸ | CDK8 | P49336 | 5/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556731 | 0.92 | CCNC (0.42) | CCNCCDK8FDPSMAOBCDK19 | |
| SCHEMBL7709222 | 0.86 | SMN1; SMN2 (0.41) | CCNCCDK8MAPTMEN1LMNA | |
| SCHEMBL2562005 | 0.84 | CCNC (0.42) | CCNCCDK8FDPSCDK19DPP4 | |
| SCHEMBL2562008 | 0.84 | CCNC (0.42) | CCNCCDK8FDPSCDK19DPP4 | |
| SCHEMBL2563026 | 0.81 | CCNC (0.40) | CCNCCDK8CDK19DPP4NPC1 | |
| SCHEMBL2559731 | 0.79 | CCNC (0.44) | CCNCCDK8MAOBCDK19DPP4 | |
| SCHEMBL2559729 | 0.79 | CCNC (0.44) | CCNCCDK8MAOBCDK19DPP4 | |
| SCHEMBL2556718 | 0.79 | CYP17A1 (0.39) | MAPTLMNANPC1RAB9ACYP1A2 | |
| SCHEMBL2557440 | 0.78 | CCNC (0.38) | CCNCCDK8FDPSCDK19DPP4 | |
| SCHEMBL2557438 | 0.78 | CCNC (0.38) | CCNCCDK8FDPSCDK19DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132051-A2 | TRICYCLE COMPOUNDS AS PHOSPHODIESTERASE-10 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-10-27 | — | — | WO | disclosed |