Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 5/20 | 0.42 |
| ▸ | CDK8 | P49336 | 5/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 4/20 | 0.38 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562005 | 1.00 | CCNC (0.42) | CCNCCDK8CDK19BRAFEIF2AK3 | |
| SCHEMBL2556731 | 0.92 | CCNC (0.42) | CCNCCDK8CDK19BRAFEIF2AK3 | |
| SCHEMBL2557438 | 0.90 | CCNC (0.38) | CCNCCDK8CDK19BRAFEIF2AK3 | |
| SCHEMBL2557440 | 0.90 | CCNC (0.38) | CCNCCDK8CDK19BRAFEIF2AK3 | |
| SCHEMBL2562733 | 0.90 | KDM4E (0.39) | CCNCCDK8BRAFEIF2AK3CYP19A1 | |
| SCHEMBL2562731 | 0.90 | KDM4E (0.39) | CCNCCDK8BRAFEIF2AK3CYP19A1 | |
| SCHEMBL2563026 | 0.88 | CCNC (0.40) | CCNCCDK8CDK19BRAFEIF2AK3 | |
| SCHEMBL2559729 | 0.88 | CCNC (0.44) | CCNCCDK8CDK19BRAFEIF2AK3 | |
| SCHEMBL2559731 | 0.88 | CCNC (0.44) | CCNCCDK8CDK19BRAFEIF2AK3 | |
| SCHEMBL2563005 | 0.84 | CCNC (0.42) | CCNCCDK8CDK19FDPSCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132051-A2 | TRICYCLE COMPOUNDS AS PHOSPHODIESTERASE-10 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-10-27 | — | — | WO | disclosed |