Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 14/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519756 | 0.92 | CETP (0.35) | CETPGPBAR1TACR1PTGDR2 | |
| SCHEMBL15519758 | 0.92 | CETP (0.35) | CETPGPBAR1TACR1PTGDR2 | |
| SCHEMBL680450 | 0.88 | CETP (0.38) | CETPGPBAR1TACR1LTC4SPTGDR2 | |
| SCHEMBL680449 | 0.88 | CETP (0.38) | CETPGPBAR1TACR1LTC4SPTGDR2 | |
| SCHEMBL679435 | 0.88 | GPBAR1 (0.36) | CETPGPBAR1TACR1PTGDR2HTR1A | |
| SCHEMBL679436 | 0.88 | GPBAR1 (0.36) | CETPGPBAR1TACR1PTGDR2HTR1A | |
| SCHEMBL680997 | 0.82 | GPBAR1 (0.40) | CETPGPBAR1LTC4SPTGDR2 | |
| SCHEMBL680996 | 0.82 | GPBAR1 (0.40) | CETPGPBAR1LTC4SPTGDR2 | |
| SCHEMBL680559 | 0.81 | GPBAR1 (0.44) | CETPGPBAR1TACR1PTGDR2 | |
| SCHEMBL680558 | 0.81 | GPBAR1 (0.44) | CETPGPBAR1TACR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2383253-B1 | METHOD FOR MANUFACTURING TRANS-{4-[(ALKYL AMINO) METHYL]CYCLOHEXYL} ACETIC ESTER | KOWA CO (JP) | 2014-03-19 | — | — | EP | disclosed |
| EP-2383253-A1 | METHOD FOR MANUFACTURING TRANS-{4-Ý(ALKYL AMINO) METHYL¨CYCLOHEXYL} ACETIC ESTER | Kowa Company, Ltd. (JP) | 2011-11-02 | — | — | EP | disclosed |