Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 14/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.30 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519758 | 1.00 | CETP (0.35) | CETPGPBAR1KDM4EPTGDR2TACR1 | |
| SCHEMBL2563087 | 0.92 | CETP (0.36) | CETPGPBAR1PTGDR2TACR1 | |
| SCHEMBL680449 | 0.88 | CETP (0.38) | CETPGPBAR1KDM4EPTGDR2TACR1 | |
| SCHEMBL680450 | 0.88 | CETP (0.38) | CETPGPBAR1KDM4EPTGDR2TACR1 | |
| SCHEMBL679435 | 0.86 | GPBAR1 (0.36) | CETPGPBAR1PTGDR2TACR1 | |
| SCHEMBL679436 | 0.86 | GPBAR1 (0.36) | CETPGPBAR1PTGDR2TACR1 | |
| SCHEMBL27763797 | 0.84 | TRPM8 (0.35) | KDM4E | |
| SCHEMBL680996 | 0.80 | GPBAR1 (0.40) | CETPGPBAR1KDM4EPTGDR2 | |
| SCHEMBL680997 | 0.80 | GPBAR1 (0.40) | CETPGPBAR1KDM4EPTGDR2 | |
| SCHEMBL27743154 | 0.80 | KDM4E (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2383253-B1 | METHOD FOR MANUFACTURING TRANS-{4-[(ALKYL AMINO) METHYL]CYCLOHEXYL} ACETIC ESTER | KOWA CO (JP) | 2014-03-19 | — | — | EP | disclosed |