SCHEMBL2563098

SCHEMBL2563098

Cc1ncc(CO)c(C(O)S)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.56
ALDH1A1 P00352 4/20 0.56
HPGD P15428 4/20 0.56
HSD17B10 Q99714 1/20 0.56
PDXK O00764 3/20 0.54
LMNA P02545 4/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
AOX1 Q06278 1/20 0.50
TRIM24 O15164 1/20 0.49
TRIM33 Q9UPN9 1/20 0.49
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
GAA P10253 2/20 0.36
GFER P55789 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
HTT P42858 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11450589 0.98 KDM4E (0.54) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL27858957 0.86 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL23045016 0.86 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10PDXK
Water SCHEMBL27615112 0.84 KDM4E (0.58) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL28084175 0.84 KDM4E (0.58) KDM4EALDH1A1HPGDHSD17B10PDXK
Hydrochloric Acid SCHEMBL28655586 0.84 KDM4E (0.58) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL28160946 0.83 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL28925356 0.83 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL27657816 0.83 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL27673816 0.83 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10PDXK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114113594-B Antigen diluent and immunodeficiency virus detection kit 上海凯创生物技术有限公司 2024-06-21 CN claimed
CN-114113594-A Antigen diluent and detection kit for immunodeficiency virus 上海凯创生物技术有限公司 2022-03-01 CN claimed
CN-114113594-B Antigen diluent and immunodeficiency virus detection kit 上海凯创生物技术有限公司 2024-06-21 CN disclosed
CN-114113594-B Antigen diluent and immunodeficiency virus detection kit 上海凯创生物技术有限公司 2024-06-21 CN disclosed
CN-114113594-A Antigen diluent and detection kit for immunodeficiency virus 上海凯创生物技术有限公司 2022-03-01 CN disclosed
CN-114113594-A Antigen diluent and detection kit for immunodeficiency virus 上海凯创生物技术有限公司 2022-03-01 CN disclosed
EP-2382199-B1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS GFBIOCHEMICALS LTD (MT) 2016-11-16 EP disclosed
US-20150175568-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS GFBIOCHEMICALS LIMITED (MT) 2015-06-25 US disclosed
US-8969559-B2 Ketal amide compounds, methods of making, and applications SEGETIS, INC. (US) 2015-03-03 US disclosed
US-20130053564-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS SEGETIS, INC. (US) 2013-02-28 US disclosed
EP-2382199-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS Segetis, Inc. (US) 2011-11-02 EP disclosed
WO-2010075330-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS SEGETIS, INC. (US) 2010-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130053564-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS KAT6A, KAT6B, KAT5 KDM4E 198/4885ALDH1A1 983/4885HPGD 1105/4885
US-20150175568-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS KAT6A, KAT6B, KAT5 KDM4E 198/4885ALDH1A1 983/4885HPGD 1105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.