SCHEMBL28084175

SCHEMBL28084175

Cc1ncc(CO)c(C(C)O)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.58
ALDH1A1 P00352 4/20 0.58
HPGD P15428 4/20 0.58
HSD17B10 Q99714 1/20 0.58
PDXK O00764 3/20 0.56
LMNA P02545 4/20 0.53
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
AOX1 Q06278 1/20 0.51
TRIM24 O15164 1/20 0.50
TRIM33 Q9UPN9 1/20 0.50
MAPT P10636 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
GAA P10253 2/20 0.37
GFER P55789 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
HTT P42858 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23045016 0.87 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL11974275 0.87 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL27858957 0.87 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10PDXK
Hydrochloric Acid SCHEMBL28655586 0.86 KDM4E (0.58) KDM4EALDH1A1HPGDHSD17B10PDXK
Water SCHEMBL27615112 0.86 KDM4E (0.58) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL27673816 0.84 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL27657816 0.84 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL28925356 0.84 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL2563098 0.84 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL28160946 0.84 KDM4E (0.56) KDM4EALDH1A1HPGDHSD17B10PDXK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117886743-A Synthetic method and purification method of 4' -O-methyl pyridoxine compound 天津科技大学 2024-04-16 CN disclosed
CN-105901476-B The method for releasing gingko toxicity based on physics and enzymatic integrated processes 南京中医药大学 2019-11-08 CN disclosed
CN-105901476-A Ginkgo toxicity removal method based on physical and enzymatic combination method 南京中医药大学 2016-08-31 CN disclosed