Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKZ | Q13574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181777 | 0.71 | PDE10A (0.39) | DGKZ | |
| SCHEMBL2556721 | 0.69 | JAK2 (0.38) | — | |
| SCHEMBL22181485 | 0.69 | PDE10A (0.37) | DGKZ | |
| SCHEMBL17548201 | 0.66 | GRM4 (0.42) | — | |
| SCHEMBL17356166 | 0.65 | MBOAT4 (0.36) | DGKZ | |
| SCHEMBL15607557 | 0.64 | PDE10A (0.40) | — | |
| SCHEMBL27929264 | 0.63 | MBOAT4 (0.35) | DGKZ | |
| SCHEMBL2556316 | 0.62 | JAK2 (0.43) | — | |
| SCHEMBL24656277 | 0.62 | PDE10A (0.36) | — | |
| SCHEMBL2564668 | 0.62 | MBOAT4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560653-A1 | CERTAIN AMINO-PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | Cytokinetics, Inc. (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011133888-A1 | CERTAIN AMINO-PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | CYTOKINETICS, INC. (US) | 2011-10-27 | — | — | WO | disclosed |