Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | QDPR | P09417 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603265 | 0.85 | MEN1 (0.37) | MEN1KMT2ACNR1MAPK1KCNH2 | |
| SCHEMBL8178812 | 0.81 | KDM4E (0.45) | MEN1KMT2ACNR1NAMPTKDM4E | |
| SCHEMBL12030754 | 0.81 | NAMPT (0.45) | MEN1KMT2AFKBP1ANAMPTALDH1A1 | |
| SCHEMBL19998528 | 0.81 | JAK1 (0.48) | MEN1KMT2AJAK1 | |
| SCHEMBL25743035 | 0.80 | MEN1 (0.41) | MEN1KMT2ACNR1KCNH2ALDH1A1 | |
| SCHEMBL104852 | 0.80 | QDPR (0.45) | KMT2AKCNH2HRH3NAMPTMAPT | |
| SCHEMBL12026425 | 0.79 | NAMPT (0.47) | MEN1KMT2AFKBP1ANAMPTALDH1A1 | |
| SCHEMBL12030751 | 0.78 | NAMPT (0.43) | KCNH2HRH3NAMPT | |
| SCHEMBL18858019 | 0.77 | ESR1 (0.39) | CNR1KCNH2HRH3FKBP1ANAMPT | |
| SCHEMBL17660297 | 0.77 | MAPT (0.39) | MEN1KMT2AKCNH2HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |