Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 6/20 | 0.56 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.53 |
| ▸ | BRAF | P15056 | 7/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25271929 | 1.00 | MEN1 (0.64) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL30457695 | 0.91 | DUSP3 (0.61) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL25633616 | 0.91 | DUSP3 (0.61) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL25633584 | 0.88 | MEN1 (0.73) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL30457573 | 0.88 | MEN1 (0.73) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL25633611 | 0.87 | MEN1 (0.48) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL30457579 | 0.86 | MEN1 (0.75) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL25633596 | 0.86 | MEN1 (0.75) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL30457568 | 0.85 | MEN1 (0.56) | MEN1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL25633601 | 0.85 | MEN1 (0.56) | MEN1KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104976-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | INSTITUT CURIE (FR) | 2023-06-15 | — | — | WO | disclosed |