Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 16/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 16/20 | 0.75 |
| ▸ | POLB | P06746 | 8/20 | 0.75 |
| ▸ | GAA | P10253 | 4/20 | 0.75 |
| ▸ | BRAF | P15056 | 2/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | GRK2 | P25098 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25633596 | 1.00 | MEN1 (0.75) | MEN1KMT2APOLBGAABRAF | |
| SCHEMBL25633584 | 0.86 | MEN1 (0.73) | MEN1KMT2APOLBGAABRAF | |
| SCHEMBL25633583 | 0.86 | MEN1 (0.64) | MEN1KMT2APOLBGAABRAF | |
| SCHEMBL25271929 | 0.86 | MEN1 (0.64) | MEN1KMT2APOLBGAABRAF | |
| SCHEMBL30457573 | 0.86 | MEN1 (0.73) | MEN1KMT2APOLBGAABRAF | |
| SCHEMBL25633601 | 0.84 | MEN1 (0.56) | MEN1KMT2APOLBGAABRAF | |
| SCHEMBL30457568 | 0.84 | MEN1 (0.56) | MEN1KMT2APOLBGAABRAF | |
| SCHEMBL30457452 | 0.82 | MEN1 (0.58) | MEN1KMT2APOLBGAABRAF | |
| SCHEMBL25633597 | 0.82 | MEN1 (0.58) | MEN1KMT2APOLBGAABRAF | |
| SCHEMBL25633592 | 0.80 | KMT2A (0.71) | MEN1KMT2APOLBGAABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051314-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | PARIS SCIENCES ET LETTRES (FR) | 2025-02-13 | — | — | US | disclosed |
| EP-4444308-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | Institut Curie (FR) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023104976-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | INSTITUT CURIE (FR) | 2023-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051314-A1 | SMALL MOLECULE INHIBITORS OF INTERFERON GAMMA SIGNALING | STAT1, IFNG, IRF2BP2 | MEN1 3227/4885KMT2A 2840/4885POLB 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.