SCHEMBL2563360

SCHEMBL2563360

CCCCC(C)(CC)CCC

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
LMNA P02545 2/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3173392 0.94 TSHR (0.38) TSHRLMNATHRBTDP1FDPS
SCHEMBL11494581 0.92 TSHR (0.37) TSHRTHRBFDPS
SCHEMBL11646996 0.88 TSHR (0.39) TSHRLMNATHRBFDPS
SCHEMBL16287051 0.88 TSHR (0.38) TSHRLMNAHSD17B10THRBTDP1
SCHEMBL598335 0.88 TSHR (0.38) TSHRLMNATHRBTDP1FDPS
SCHEMBL17420817 0.88 TSHR (0.38) TSHRLMNAHSD17B10THRBTDP1
SCHEMBL598167 0.87 TSHR (0.40) TSHRLMNAHSD17B10TDP1
SCHEMBL643038 0.86 LMNA (0.31) LMNAHSD17B10
SCHEMBL1116095 0.86 TSHR (0.44) TSHRTHRBFDPS
SCHEMBL1116285 0.86 TSHR (0.44) TSHRTHRBFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3481885-B1 HIGH-SOLIDS CONTENT SOLVENT-BASED ADHESIVE COMPOSITIONS AND METHODS OF MAKING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-09-13 EP claimed
EP-3481879-B1 TWO-COMPONENT ADHESIVE COMPOSITIONS AND METHODS OF MAKING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-12-22 EP claimed
EP-2410971-B1 RADIATION-CURING, HIGHLY FUNCTIONAL POLYURETHANE (METH)ACRYLATE BASF SE (DE) 2017-08-16 EP claimed
EP-2217651-B1 CURABLE COMPOSITIONS CONTAINING ISOCYANATE-BASED TOUGHENERS HENKEL AG & CO KGAA (DE) 2013-08-28 EP claimed
EP-1134247-B1 Highfunctionality polyisocyanates BASF AG (DE) 2007-09-12 EP claimed
EP-1026185-B1 Dendrimers and highly branched polyurethanes BASF AG (DE) 2005-02-16 EP claimed
EP-0668271-B1 Process for the preparation of isocyanurate-group containing polyisocyanates BASF AG (DE) 2002-01-16 EP claimed
US-20010005738-A1 Building blocks containing isocyanate groups and their use for functionalizing or modifying compounds or surfaces BASF AKTIENGESELLSCHAFT (DE) 2001-06-28 US claimed
WO-2023121907-A1 APPARATUS AND METHOD FOR APPLYING A FOAMING REACTION MIXTURE ONTO A LAMINATOR USING A DIVERGING NOZZLE DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-29 WO disclosed
WO-2023088793-A1 PREPARATION OF POLYISOCYANATES CONTAINING IMINOOXADIAZINEDIONE GROUPS AND THEIR USE BASF SE (DE) 2023-05-25 WO disclosed
CN-112041364-B Two-component adhesive composition based on phosphate-modified isocyanates and method for the production thereof 陶氏环球技术有限责任公司 2022-11-11 CN disclosed
CN-111434700-B Star block copolymer and process for producing the same 中国石油化工股份有限公司 2022-09-20 CN disclosed
CN-112646098-B Block copolymer and process for producing the same 中国石油化工股份有限公司 2022-09-20 CN disclosed
CN-110229293-B Star block copolymer and preparation method thereof 中国石油化工股份有限公司 2022-06-21 CN disclosed
US-5717003-A LATENT ACID CATALYST CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-02-10 US disclosed
CN-1135493-A Pressure isocyanate semi-prepolymer mixture containing foaming agent, and based on lignin-polyether polyalcohol ELASTOGRAN GMBH (DE) 1996-11-13 CN disclosed
CN-1132138-A Production of rigid polyurethane foams having reduced thermal conductivity, and use thereof ELASTOGRAN GMBH (DE) 1996-10-02 CN disclosed
EP-0449110-B1 2,2-Dialkylpentane-1,5-diisocyanates, -diurethanes, and -dicarbamic acid chlorides, process for their preparation and their use BASF AG (DE) 1996-06-05 EP disclosed
EP-0449110-A2 2,2-Dialkylpentane-1,5-diisocyanates, -diurethanes, and -dicarbamic acid chlorides, process for their preparation and their use BASF Aktiengesellschaft (DE) 1991-10-02 EP disclosed
EP-0328158-A1 A method for improving the release of a cast concrete item from the mould by applying to the mould a mould release composition CASTROL A/S (DK) 1989-08-16 EP disclosed