Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799426 | 0.92 | HSD17B10 (0.50) | MEN1CYP3A4KMT2AHSD17B10KDM4E | |
| SCHEMBL13942270 | 0.92 | HSD17B10 (0.50) | MEN1CYP3A4KMT2AHSD17B10KDM4E | |
| SCHEMBL22631568 | 0.92 | HSD17B10 (0.50) | MEN1CYP3A4KMT2AHSD17B10KDM4E | |
| SCHEMBL27214337 | 0.92 | HSD17B10 (0.50) | MEN1CYP3A4KMT2AHSD17B10KDM4E | |
| SCHEMBL13899513 | 0.92 | HSD17B10 (0.50) | MEN1CYP3A4KMT2AHSD17B10KDM4E | |
| SCHEMBL17798578 | 0.92 | HSD17B10 (0.50) | MEN1CYP3A4KMT2AHSD17B10KDM4E | |
| SCHEMBL25633170 | 0.92 | HSD17B10 (0.50) | MEN1CYP3A4KMT2AHSD17B10KDM4E | |
| SCHEMBL21569127 | 0.87 | CYP3A4 (0.45) | MEN1CYP3A4KMT2AHSD17B10KDM4E | |
| SCHEMBL24455470 | 0.83 | CYP2D6 (0.50) | MEN1CYP3A4KMT2AHSD17B10TP53 | |
| SCHEMBL24455282 | 0.83 | CYP2D6 (0.50) | MEN1CYP3A4KMT2AHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SEAGEN INC (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173093-A1 | CHARGE VARIANT LINKERS | SSB, UACA, CDA | MEN1 515/4885CYP3A4 4396/4885KMT2A 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.