Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 19/20 | 0.74 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.65 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2557647 | 0.99 | TTK (0.73) | TTKMAPK8MAP2K4 | |
| Trifluoroacetic Acid SCHEMBL2555732 | 0.90 | TTK (0.65) | TTKMAPK8MAP2K4 | |
| SCHEMBL2568971 | 0.88 | TTK (0.58) | TTKMAPK8MAP2K4 | |
| SCHEMBL2566947 | 0.85 | TTK (0.73) | TTKMAPK8MAP2K4 | |
| SCHEMBL2567517 | 0.85 | TTK (1.00) | TTKMAPK8MAP2K4 | |
| SCHEMBL2564335 | 0.85 | TTK (1.00) | TTKMAPK8MAP2K4 | |
| Hydrochloric Acid SCHEMBL2577139 | 0.84 | TTK (0.71) | TTKMAPK8MAP2K4 | |
| SCHEMBL2564024 | 0.83 | TTK (0.70) | TTKMAPK8MAP2K4 | |
| SCHEMBL12281363 | 0.82 | TTK (1.00) | TTKMAPK8MAP2K4 | |
| SCHEMBL2561009 | 0.82 | TTK (0.72) | TTKMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |