Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24607305 | 0.86 | NPC1 (0.48) | NPC1HRH3DRD2GNAI3GNAO1 | |
| SCHEMBL24661412 | 0.85 | SMN1; SMN2 (0.41) | NPC1HRH3CARM1PRMT6TMEM97 | |
| SCHEMBL25972078 | 0.83 | NPC1 (0.46) | NPC1HRH3DRD2GNAI3GNAO1 | |
| SCHEMBL20234299 | 0.81 | NPC1 (0.41) | NPC1HRH3CARM1PRMT6TMEM97 | |
| SCHEMBL21214843 | 0.81 | NPC1 (0.41) | NPC1HRH3DRD2CARM1PRMT6 | |
| SCHEMBL23970916 | 0.80 | NCF1 (0.46) | NPC1HRH3 | |
| SCHEMBL22477411 | 0.80 | HRH3 (0.45) | NPC1HRH3DRD2GNAI3GNAO1 | |
| SCHEMBL27013893 | 0.80 | NPC1 (0.43) | NPC1HRH3DRD2CARM1PRMT6 | |
| SCHEMBL22856368 | 0.79 | NPC1 (0.42) | NPC1HRH3DRD2CARM1PRMT6 | |
| SCHEMBL18551309 | 0.79 | CARM1 (0.50) | HRH3CARM1PRMT6TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097251-A1 | OLIGONUCLEOTIDE-CONTAINING TRANSCRIPTION FACTOR TARGETING CHIMERAS | YALE UNIVERSITY (US) | 2023-06-01 | — | — | WO | disclosed |