Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983072 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP3A4RECQLGAA | |
| SCHEMBL9794409 | 0.86 | MAPT (0.41) | ALDH1A1TSHRCYP3A4RECQLGAA | |
| SCHEMBL215155 | 0.83 | CYP1A2 (0.41) | ALDH1A1TSHRCYP3A4RECQLGAA | |
| SCHEMBL25637794 | 0.82 | KDM4E (0.42) | ALDH1A1TSHRCYP3A4KDM4EMEN1 | |
| SCHEMBL19171917 | 0.80 | MERTK (0.42) | ALDH1A1TSHRCYP3A4KDM4EMAPT | |
| SCHEMBL10781069 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CYP3A4KDM4EMEN1MAPT | |
| SCHEMBL25337052 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP3A4RECQLGAA | |
| SCHEMBL31597058 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP3A4RECQLGAA | |
| SCHEMBL15514790 | 0.78 | POLB (0.43) | ALDH1A1CYP3A4GAAKDM4EMAPT | |
| SCHEMBL12354210 | 0.78 | CYP1A2 (0.40) | ALDH1A1TSHRCYP3A4GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192734-A1 | TRICYCLIC COMPOUNDS AS EGFR INHIBITORS | QILU PHARMACEUTICAL CO LTD (CN) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192734-A1 | TRICYCLIC COMPOUNDS AS EGFR INHIBITORS | EGFR, ERBB2, ERBB3 | ALDH1A1 3656/4885TSHR 1375/4885CYP3A4 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.