Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | ALPI | P09923 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALPG | P10696 | 2/20 | 0.50 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284420 | 0.81 | TAAR1 (0.59) | TAAR1ALPLMAPK1KMT2AALDH1A1 | |
| SCHEMBL630978 | 0.81 | TAAR1 (0.63) | TAAR1ALPLMAPK1CYP3A4CYP2D6 | |
| SCHEMBL1001310 | 0.80 | TAAR1 (0.62) | TAAR1ALPLMAPK1CYP2D6CYP2C9 | |
| SCHEMBL6756155 | 0.79 | TAAR1 (0.56) | TAAR1ALPLMAPK1KMT2AALDH1A1 | |
| SCHEMBL24357951 | 0.79 | TAAR1 (0.47) | TAAR1ALPLMAPK1CYP3A4CYP2D6 | |
| SCHEMBL19509208 | 0.78 | TAAR1 (0.49) | TAAR1ALPLMAPK1CYP3A4CYP2D6 | |
| SCHEMBL9519998 | 0.77 | TAAR1 (0.55) | TAAR1ALPLMAPK1KMT2AALDH1A1 | |
| SCHEMBL7098832 | 0.77 | IDO1 (0.57) | TAAR1ALPLMAPK1KMT2AALDH1A1 | |
| SCHEMBL15085764 | 0.77 | TAAR1 (0.55) | TAAR1ALPLMAPK1KMT2AALDH1A1 | |
| SCHEMBL11319085 | 0.77 | CYP3A4 (0.51) | TAAR1ALPLMAPK1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11680064-B2 | Capsid inhibitors for the treatment of HIV | GILEAD SCIENCES, INC. (US) | 2023-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11680064-B2 | Capsid inhibitors for the treatment of HIV | HAVCR2, MAVS, CD4 | TAAR1 4782/4885ALPL 4559/4885MAPK1 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.