SCHEMBL25640280

SCHEMBL25640280

CNCC1(F)CCN(C2CCOCC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 18/20 0.39
KCNH2 Q12809 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25640276 0.83
SCHEMBL24774512 0.75 HRH3 (0.37) HRH3KCNH2
SCHEMBL23323156 0.74
SCHEMBL24737029 0.74 HRH3 (0.36) HRH3KCNH2
SCHEMBL24775986 0.74 HRH3 (0.40) HRH3KCNH2
SCHEMBL18202974 0.71 HRH3 (0.46) HRH3
SCHEMBL17233316 0.69 HRH3 (0.42) HRH3KCNH2
SCHEMBL15739795 0.69 KDM1A (0.44)
SCHEMBL23944123 0.69 HRH3 (0.32) HRH3
SCHEMBL21648795 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023104043-A1 ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF 杭州和正医药有限公司 2023-06-15 WO disclosed