Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24774834 | 0.85 | CNR2 (0.32) | HRH3 | |
| SCHEMBL24774512 | 0.76 | HRH3 (0.37) | HRH3MEN1NPC1GAAMAPT | |
| SCHEMBL24737029 | 0.75 | HRH3 (0.36) | HRH3MEN1NPC1GAAMAPT | |
| SCHEMBL24775986 | 0.75 | HRH3 (0.40) | HRH3MEN1NPC1GAAMAPT | |
| SCHEMBL24774509 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL25481364 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL19747700 | 0.69 | HRH3 (0.35) | HRH3 | |
| SCHEMBL25640280 | 0.69 | HRH3 (0.39) | HRH3 | |
| SCHEMBL12518135 | 0.68 | — | — | |
| SCHEMBL8267935 | 0.67 | KDM1A (0.34) | GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |