Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17864792 | 0.99 | KDM4E (0.63) | KDM4ETDP1L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL17982837 | 0.89 | RXFP1 (0.55) | KDM4ETDP1L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL348999 | 0.89 | MAPT (0.64) | KDM4EL3MBTL1RXFP1ALDH1A1MEN1 | |
| SCHEMBL7359117 | 0.88 | ALDH1A1 (0.58) | KDM4ETDP1L3MBTL1ALDH1A1ALDH1A3 | |
| SCHEMBL29953174 | 0.87 | CYP1A2 (0.57) | KDM4ETDP1L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL24234716 | 0.86 | KDM4E (0.50) | KDM4ETDP1L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL15330421 | 0.85 | RXFP1 (0.52) | KDM4ETDP1L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL2562461 | 0.84 | MAPT (0.50) | KDM4ETDP1L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL15332886 | 0.82 | RXFP1 (0.52) | KDM4ETDP1L3MBTL1RXFP1ALDH1A1 | |
| SCHEMBL2556584 | 0.82 | NPC1 (0.50) | KDM4ETDP1L3MBTL1RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101606933-A | Dihydro porphin photosensitizer and preparation thereof and application | UNIV DONGHUA (CN) | 2009-12-23 | — | — | CN | claimed |
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |
| CN-101606933-A | Dihydro porphin photosensitizer and preparation thereof and application | UNIV DONGHUA (CN) | 2009-12-23 | — | — | CN | disclosed |