Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25478847 | 0.87 | TACR1 (0.40) | TACR1CHRM2KDM4E | |
| SCHEMBL25640512 | 0.86 | KMT2A (0.41) | TACR1GNAI3MEN1KMT2A | |
| SCHEMBL25640516 | 0.85 | TACR1 (0.42) | TACR1MEN1KMT2AKDM4E | |
| SCHEMBL25264678 | 0.85 | KMT2A (0.43) | MEN1KMT2AKDM4EPDE10A | |
| SCHEMBL23943614 | 0.85 | KMT2A (0.46) | MEN1KMT2AKDM4E | |
| SCHEMBL30034375 | 0.85 | KMT2A (0.46) | MEN1KMT2AKDM4E | |
| SCHEMBL25192315 | 0.85 | KMT2A (0.46) | MEN1KMT2AKDM4E | |
| SCHEMBL25189507 | 0.85 | KMT2A (0.43) | MEN1KMT2AKDM4EPDE10A | |
| SCHEMBL25478885 | 0.85 | TACR1 (0.38) | TACR1GNAI3CHRM2KMT2AKDM4E | |
| SCHEMBL25640410 | 0.85 | TACR1 (0.38) | TACR1GNAI3CHRM2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |