Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 4/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25478885 | 1.00 | TACR1 (0.38) | TACR1OPRD1CYP1A2CHRM2SLC6A4 | |
| SCHEMBL25640466 | 0.95 | TACR1 (0.37) | TACR1OPRD1CYP1A2CHRM2SLC6A4 | |
| SCHEMBL25478847 | 0.85 | TACR1 (0.40) | TACR1OPRD1CYP1A2CHRM2SLC6A4 | |
| SCHEMBL25640464 | 0.85 | TACR1 (0.47) | TACR1CHRM2KDM4EGNAI3KMT2A | |
| SCHEMBL25640540 | 0.83 | LMNA (0.48) | RECQLALDH1A1LMNAKMT2A | |
| SCHEMBL25192315 | 0.81 | KMT2A (0.46) | KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL23943614 | 0.81 | KMT2A (0.46) | KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL30034375 | 0.81 | KMT2A (0.46) | KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL25479953 | 0.81 | TACR1 (0.35) | TACR1OPRD1CYP1A2CHRM2SLC6A4 | |
| SCHEMBL25640512 | 0.80 | KMT2A (0.41) | TACR1TSHRGNAI3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |