SCHEMBL25640799

SCHEMBL25640799

c1cc(-c2ccc3c(c2)-c2ccccc2-c2ccccc2-c2ccccc2-3)cc(-c2nc(-n3c4ccccc4c4ccccc43)nc(-n3c4ccccc4c4ccccc43)n2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 1/20 0.38
APAF1 O14727 1/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.38
XBP1 P17861 1/20 0.38
PTBP1 P26599 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
GALK1 P51570 1/20 0.38
BLM P54132 1/20 0.38
SMAD3 P84022 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
DUSP3 P51452 1/20 0.34
KDM4E B2RXH2 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25640766 0.94 ATM (0.36) ATML3MBTL1MAPTSMN1; SMN2MEN1
SCHEMBL25640782 0.90 MEN1 (0.39) ATML3MBTL1MAPTSMN1; SMN2MEN1
SCHEMBL14426195 0.90 KDM4E (0.37) ATML3MBTL1MEN1KMT2AKDM4E
SCHEMBL14426202 0.89 KDM4E (0.39) ATML3MBTL1MAPTMEN1LMNA
SCHEMBL14426194 0.88 KDM4E (0.36) ATML3MBTL1MAPTMEN1LMNA
SCHEMBL14426201 0.88 KDM4E (0.36) ATML3MBTL1MAPTMEN1LMNA
SCHEMBL25661268 0.88 KDM4E (0.40) ATML3MBTL1MAPTMEN1LMNA
SCHEMBL25661269 0.88 KDM4E (0.40) ATML3MBTL1MAPTMEN1LMNA
SCHEMBL14426191 0.88 KDM4E (0.36) ATML3MBTL1MAPTMEN1LMNA
SCHEMBL25661225 0.88 KDM4E (0.40) ATML3MBTL1MAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192665-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230192665-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192665-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 ATM 4109/4885L3MBTL1 589/4885MAPT 1201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.