Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 10/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.35 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.35 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12463566 | 0.75 | ACHE (0.50) | PARP1PARP10PARP11PDPK1ACHE | |
| SCHEMBL27340828 | 0.72 | PARP10 (0.54) | PARP1PARP10PARP11PDPK1ACHE | |
| SCHEMBL16097877 | 0.66 | PARP10 (0.49) | PARP1PARP10PARP11PDPK1 | |
| SCHEMBL31749685 | 0.66 | PARP10 (0.54) | PARP1PARP10PARP11GSK3BPDPK1 | |
| SCHEMBL19153427 | 0.66 | PARP10 (0.57) | PARP1PARP10PARP11PDPK1ACHE | |
| SCHEMBL29463796 | 0.65 | FABP6 (0.60) | PARP1PARP10PARP11GSK3BPDPK1 | |
| SCHEMBL352852 | 0.65 | FABP6 (0.60) | PARP1PARP10PARP11GSK3BPDPK1 | |
| SCHEMBL2260720 | 0.65 | GSK3A (0.41) | GSK3AGSK3B | |
| SCHEMBL30229191 | 0.65 | FABP6 (0.44) | GSK3B | |
| SCHEMBL15330821 | 0.65 | PARP1 (0.60) | PARP1PARP10PARP11PDPK1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107722-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |