Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29262775 | 0.91 | LMNA (0.71) | LMNASMN1; SMN2L3MBTL1HTTTPSAB1 | |
| SCHEMBL8861893 | 0.83 | HTT (0.54) | SMN1; SMN2ACHEHTTHDAC8HDAC3 | |
| SCHEMBL966830 | 0.83 | TDP1 (0.60) | LMNASMN1; SMN2ACHEL3MBTL1HTT | |
| SCHEMBL2567987 | 0.81 | TDP1 (0.61) | SMN1; SMN2ACHEL3MBTL1TDP1 | |
| SCHEMBL2565857 | 0.81 | TDP1 (0.61) | SMN1; SMN2ACHEL3MBTL1TDP1 | |
| SCHEMBL2567938 | 0.81 | TDP1 (0.61) | SMN1; SMN2ACHEL3MBTL1TDP1 | |
| SCHEMBL20492122 | 0.80 | TDP1 (0.65) | SMN1; SMN2ACHEL3MBTL1TDP1 | |
| SCHEMBL7372302 | 0.80 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2L3MBTL1HTTTGM2 | |
| SCHEMBL18951926 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2ACHEHTTALDH1A1 | |
| SCHEMBL30823376 | 0.79 | SMN1; SMN2 (0.97) | LMNASMN1; SMN2L3MBTL1HTTTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013183-B1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXIETHYL)PHENOL AS AGONISTS OF THE BETA2 ADRENERGIC RECEPTOR | ALMIRALL SA (ES) | 2011-11-02 | — | — | EP | disclosed |
| EP-2013183-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXIETHYL)PHENOL AS AGONISTS OF THE BETA2 ADRENERGIC RECEPTOR | Laboratorios Almirall, S.A. (ES) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007124898-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXIETHYL)PHENOL AS AGONISTS OF THE β2 ADRENERGIC RECEPTOR | LABORATORIOS, ALMIRALL S.A. (ES) | 2007-11-08 | — | — | WO | disclosed |