Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25647817 | 0.87 | KMT2A (0.35) | KMT2AMEN1PDE9ACTSDHTR3A | |
| SCHEMBL25647819 | 0.84 | KMT2A (0.34) | KMT2AMEN1PDE9ACTSDF2 | |
| SCHEMBL25647779 | 0.81 | KMT2A (0.36) | KMT2AMEN1PDE9ACTSDHTR3A | |
| SCHEMBL30449087 | 0.74 | BTK (0.41) | — | |
| SCHEMBL25228011 | 0.74 | BTK (0.41) | — | |
| SCHEMBL30449840 | 0.74 | KMT2A (0.40) | KMT2AMEN1PDE9AHTR3AMAPT | |
| SCHEMBL25228606 | 0.74 | KMT2A (0.40) | KMT2AMEN1PDE9AHTR3AMAPT | |
| SCHEMBL25647778 | 0.73 | TPH1 (0.34) | KMT2AMEN1PDE9ACTSDF2 | |
| SCHEMBL25647843 | 0.71 | PDE9A (0.36) | KMT2AMEN1PDE9ACTSDPOLB | |
| SCHEMBL22902838 | 0.69 | CYP1A2 (0.38) | KMT2AMEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110936-A1 | REVERSIBLE MACROCYCLIC KINASE INHIBITORS | NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) | 2023-06-22 | — | — | WO | disclosed |