Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.85 |
| ▸ | LCK | P06239 | 18/20 | 0.85 |
| ▸ | BTK | Q06187 | 4/20 | 0.85 |
| ▸ | EGFR | P00533 | 10/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25649436 | 1.00 | JAK3 (0.85) | JAK3LCKBTKEGFR | |
| SCHEMBL16765129 | 0.92 | JAK3 (1.00) | JAK3LCKBTKEGFR | |
| SCHEMBL25593701 | 0.92 | JAK3 (1.00) | JAK3LCKBTKEGFR | |
| SCHEMBL16765130 | 0.92 | JAK3 (1.00) | JAK3LCKBTKEGFR | |
| SCHEMBL28642729 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL21855159 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL32670362 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL20867721 | 0.92 | JAK3 (0.89) | JAK3LCKBTKEGFR | |
| SCHEMBL21946330 | 0.92 | JAK3 (0.86) | JAK3LCKBTKEGFR | |
| SCHEMBL24891001 | 0.91 | JAK3 (0.88) | JAK3LCKBTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |