Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.87 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.66 |
| ▸ | PGR | P06401 | 14/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291767 | 0.94 | NR3C1 (0.75) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL446911 | 0.93 | NR3C1 (1.00) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL9987504 | 0.88 | NR3C1 (0.67) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL292324 | 0.83 | NR3C1 (0.70) | NR3C1NR3C2PGR | |
| SCHEMBL6385323 | 0.83 | NR3C1 (0.74) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL292256 | 0.83 | NR3C1 (0.74) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL290958 | 0.82 | NR3C1 (0.77) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL15104425 | 0.81 | NR3C1 (0.71) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL1932022 | 0.81 | NR3C1 (0.57) | NR3C1CYP3A4NR3C2PGR | |
| SCHEMBL9987502 | 0.81 | NR3C1 (0.57) | NR3C1CYP3A4NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051710-B1 | COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, OR ALLEVIATING POSTERIOR-SEGMENT OPHTHALMIC DISEASES | BAUSCH & LOMB (US) | 2011-11-02 | — | — | EP | disclosed |