Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343998 | 1.00 | KMT2A (0.56) | KMT2AHTTPREPTGM2PNMT | |
| SCHEMBL8642710 | 0.99 | KMT2A (0.54) | KMT2AHTTPREPTGM2PNMT | |
| SCHEMBL8046430 | 0.96 | KMT2A (0.52) | KMT2AHTTPREPTGM2PNMT | |
| SCHEMBL28586408 | 0.95 | HTT (0.57) | KMT2AHTTPREPTGM2PNMT | |
| SCHEMBL4663188 | 0.92 | KMT2A (0.46) | KMT2AHTTPREPTGM2PNMT | |
| SCHEMBL29541016 | 0.91 | HTT (0.47) | KMT2AHTTPNMTFOLH1DRD2 | |
| SCHEMBL6030527 | 0.91 | HTT (0.47) | KMT2AHTTPNMTFOLH1DRD2 | |
| SCHEMBL6036900 | 0.89 | PNMT (0.48) | KMT2AHTTPREPTGM2PNMT | |
| SCHEMBL230689 | 0.87 | PNMT (0.45) | KMT2AHTTPREPTGM2PNMT | |
| Succinic Acid SCHEMBL28812246 | 0.87 | HTT (0.43) | KMT2AHTTPNMTFOLH1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167599-B | Compounds comprising self-sacrificing linking groups incorporating beta-galactosides | 英托赛尔公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-115192730-A | Bispecific polypeptide nano-drug targeting PD-L1 and preparation method and application thereof | 郑州大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-110746490-B | Polypeptide composition for blocking immune check point based on click reaction and preparation method and application thereof | 国家纳米科学中心 | 2021-09-07 | — | — | CN | disclosed |
| CN-111349145-A | Polypeptide molecule for preventing PD-L1 from being redistributed on tumor surface, preparation and application | 北京工业大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-110746490-A | Polypeptide composition for blocking immune check point based on click reaction and preparation method and application thereof | 国家纳米科学中心 | 2020-02-04 | — | — | CN | disclosed |
| EP-2560687-A2 | COMPOSITIONS AND METHODS FOR SELECTIVE DELIVERY OF OLIGONUCLEOTIDE MOLECULES TO SPECIFIC NEURON TYPES | Nlife Therapeutics S.L. (ES) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011131693-A2 | COMPOSITIONS AND METHODS FOR SELECTIVE DELIVERY OF OLIGONUCLEOTIDE MOLECULES TO SPECIFIC NEURON TYPES | NLIFE THERAPEUTICS, S.L. (ES) | 2011-10-27 | — | — | WO | disclosed |