⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25757587 | 0.93 | — | — | |
| SCHEMBL25757460 | 0.91 | — | — | |
| SCHEMBL25274537 | 0.90 | — | — | |
| SCHEMBL25274538 | 0.90 | — | — | |
| SCHEMBL25227764 | 0.90 | — | — | |
| SCHEMBL25758426 | 0.89 | — | — | |
| SCHEMBL25278285 | 0.88 | — | — | |
| SCHEMBL25279246 | 0.88 | CTSV (0.62) | — | |
| SCHEMBL25270645 | 0.88 | CTSV (0.75) | — | |
| SCHEMBL25279245 | 0.88 | CTSV (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074938-A1 | CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2025-03-06 | — | — | US | disclosed |
| US-20230192660-A1 | Protease Inhibitors for Treatment or Prevention of Coronavirus Disease | UNIV LELAND STANFORD JUNIOR (US) | 2023-06-22 | — | — | US | disclosed |
| WO-2023114516-A2 | CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114516-A2 | CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-06-22 | — | — | WO | disclosed |