Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26565527 | 0.86 | HPGD (0.40) | ALDH1A1KDM4EPOLBSMN1; SMN2MEN1 | |
| SCHEMBL2671455 | 0.75 | CYP1A2 (0.56) | ALDH1A1KDM4EPOLBSMN1; SMN2MEN1 | |
| SCHEMBL2671454 | 0.75 | CYP1A2 (0.56) | ALDH1A1KDM4EPOLBSMN1; SMN2MEN1 | |
| SCHEMBL20415711 | 0.70 | KDM4E (0.39) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL17221126 | 0.70 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL17221128 | 0.70 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL17221124 | 0.70 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL20227828 | 0.69 | MAPT (0.54) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL3896958 | 0.69 | MAPT (0.54) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL3896955 | 0.69 | MAPT (0.54) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102378-A1 | MACROCYCLIC COMPOUNDS HAVING FARNESYLTRANSFERASE INHIBITORY ACTIVITY | KURA ONCOLOGY, INC. (US) | 2023-06-08 | — | — | WO | disclosed |