Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328550 | 0.73 | F2 (0.48) | ALDH1A1LMNARAB9ANPC1MAPT | |
| SCHEMBL11391147 | 0.68 | CA1 (0.64) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL8233564 | 0.67 | GAA (0.77) | KMT2ALMNARAB9ANPC1MAPT | |
| SCHEMBL23600 | 0.66 | CA1 (0.80) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL28993944 | 0.66 | CA1 (0.80) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| SCHEMBL12160355 | 0.65 | CA1 (0.59) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL988147 | 0.65 | MAPT (0.70) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL12314004 | 0.65 | MAPT (0.58) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11772472 | 0.64 | CA1 (0.70) | ALDH1A1KDM4EMEN1KMT2ARAB9A | |
| Water SCHEMBL22720573 | 0.64 | CA1 (0.76) | ALDH1A1KDM4EMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042920-A1 | IMIDAZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | OCEAN UNIVERSITY OF CHINA (CN) | 2025-02-06 | — | — | US | disclosed |
| EP-4442692-A1 | IMIDAZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Ocean University of China (CN) | 2024-10-09 | — | — | EP | disclosed |
| WO-2023093700-A1 | IMIDAZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 中国海洋大学 | 2023-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042920-A1 | IMIDAZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | WEE2, WEE1, GCK | ALDH1A1 1591/4885KDM4E 1398/4885MEN1 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.