Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20660787 | 0.81 | F2 (0.46) | F2PLAUKLKB1ELANERAB9A | |
| SCHEMBL7056151 | 0.78 | F2 (0.48) | F2PLAUKLKB1ELANERAB9A | |
| SCHEMBL7056155 | 0.78 | F2 (0.48) | F2PLAUKLKB1ELANERAB9A | |
| SCHEMBL24937400 | 0.78 | L3MBTL1 (0.56) | F2PLAUKLKB1ELANERAB9A | |
| SCHEMBL31460083 | 0.76 | F2 (0.47) | F2PLAUKLKB1ELANERAB9A | |
| SCHEMBL30829495 | 0.75 | F2 (0.46) | F2PLAUKLKB1ELANERAB9A | |
| SCHEMBL24875516 | 0.74 | F2 (0.44) | F2PLAUKLKB1ELANERAB9A | |
| SCHEMBL25653535 | 0.73 | ALDH1A1 (0.73) | RAB9ANPC1LMNAMAPTCA1 | |
| SCHEMBL16427745 | 0.73 | PDE4B (0.50) | LMNAMAPTHTTALDH1A1HPGD | |
| SCHEMBL17221597 | 0.73 | MAPT (0.47) | F2PLAUKLKB1ELANERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |