Oxirane

Oxirane

SCHEMBL2565430

C1CO1.OCC(CO)(CO)CCOCCC(CO)(CO)CO

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2317873 0.87 TSHR (0.39) TSHRMAPK1
SCHEMBL3839562 0.79 TSHR (0.56) TSHRMAPK1
SCHEMBL29046161 0.77 TSHR (0.32) TSHRMAPK1
SCHEMBL11670277 0.77 MEN1 (0.58) TSHRMAPK1
SCHEMBL1236601 0.75 TSHR (0.37) TSHRMAPK1
Oxirane SCHEMBL524300 0.74 ALDH1A1 (0.39) TSHR
Oxirane SCHEMBL1717397 0.74 ALDH1A1 (0.39) TSHR
Oxirane SCHEMBL1006448 0.74 ALDH1A1 (0.30) TSHR
SCHEMBL8431703 0.74 ALDH1A1 (0.30) TSHR
SCHEMBL4434713 0.73 MEN1 (0.37) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1400856-B1 Method of making lithographic printing plate FUJIFILM CORP (JP) 2011-11-02 EP claimed
US-7081330-B2 Method of making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2006-07-25 US claimed
US-20040063036-A1 Method of making lithographic printing plate FUJI PHOTO FILM CO., LTD. 2004-04-01 US claimed
EP-1400856-A2 Method of making lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2004-03-24 EP claimed