Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 8/20 | 0.42 |
| ▸ | BLM | P54132 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GABRR2 | P28476 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL28793643 | 0.96 | — | — | |
| Ethylenediamine SCHEMBL28793642 | 0.96 | GLRA1 (0.50) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Ethylenediamine SCHEMBL10815460 | 0.91 | GLRA1 (0.54) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Ethylenediamine SCHEMBL28229848 | 0.91 | GLRA1 (0.54) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Ethylenediamine SCHEMBL7510435 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL909940 | 0.91 | GLRA1 (0.54) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Ethylenediamine SCHEMBL6428356 | 0.91 | GLRA1 (0.54) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Ethylenediamine SCHEMBL28314045 | 0.87 | — | — | |
| Acetic Acid SCHEMBL28214497 | 0.85 | FFAR3 (0.50) | GLRA1SLC6A9OR51E2GABRR1BLM | |
| Oxalic Acid SCHEMBL28209749 | 0.83 | OR51E2 (0.47) | GLRA1SLC6A9OR51E2GABRR1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861302-B1 | COATABLE BIOCIDAL COMPOSITIONS | MINNESOTA MINING & MFG (US) | 2001-11-07 | — | — | EP | claimed |
| EP-0861302-A1 | COATABLE BIOCIDAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997003135-A1 | COATABLE BIOCIDAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-01-30 | — | — | WO | claimed |
| US-5585407-A | SUSTAINED RELEASE OF MICROBIOCIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-17 | — | — | US | claimed |
| EP-3041902-B1 | AQUEOUS POLYURETHANE DISPSERSIONS | ROHM & HAAS (US) | 2018-07-25 | — | — | EP | disclosed |
| US-9668476-B2 | Removable antimicrobial coating compositions and methods of use | LANXESS CORPORATION (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160286796-A1 | REMOVABLE COATING COMPOSITION | THE CHEMOURS COMPANY FC, LLC | 2016-10-06 | — | — | US | disclosed |
| US-20130239896-A1 | METHODS AND COMPOSITIONS FOR TREATED FERTILIZED AVIAN EGGS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-09-19 | — | — | US | disclosed |
| EP-2381766-B1 | METHODS AND COMPOSITIONS FOR TREATING FERTILIZED AVIAN EGGS | DU PONT (US) | 2013-09-18 | — | — | EP | disclosed |
| EP-2381766-A1 | METHODS AND COMPOSITIONS FOR TREATING FERTILIZED AVIAN EGGS | E. I. du Pont de Nemours and Company (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010101679-A1 | METHODS AND COMPOSITIONS FOR TREATING FERTILIZED AVIAN EGGS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-10 | — | — | WO | disclosed |
| US-20100186674-A1 | METHODS AND COMPOSITIONS FOR TREATING FERTILIZED AVIAN EGGS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-29 | — | — | US | disclosed |
| WO-2007100654-A2 | REMOVABLE ANTIMICROBIAL COATING COMPOSITIONS AND METHODS OF USE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-09-07 | — | — | WO | disclosed |
| EP-0861302-B1 | COATABLE BIOCIDAL COMPOSITIONS | MINNESOTA MINING & MFG (US) | 2001-11-07 | — | — | EP | disclosed |
| EP-0861302-A1 | COATABLE BIOCIDAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997003135-A1 | COATABLE BIOCIDAL COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-01-30 | — | — | WO | disclosed |
| US-5585407-A | SUSTAINED RELEASE OF MICROBIOCIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0228481-B1 | COATING COMPOSITION | YUHO CHEMICALS INC. (JP) | 1992-07-15 | — | — | EP | disclosed |
| EP-0228481-A1 | Coating composition | YUHO CHEMICALS INC. (JP) | 1987-07-15 | — | — | EP | disclosed |
| US-4622360-A | FLOORS, POLYURETHANE CONTAINING CARBOXYLATE GROUPS CROSSLINKED WITH METAL | YUHO CHEMICALS INC. (JP) | 1986-11-11 | — | — | US | disclosed |