Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 8/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25656110 | 0.90 | ENPP1 (0.80) | ENPP1AURKAACHEBACE1MAPK1 | |
| SCHEMBL25656114 | 0.88 | ENPP1 (0.67) | ENPP1AURKALMNAACHEBACE1 | |
| SCHEMBL25656115 | 0.80 | ENPP1 (0.50) | ENPP1AURKALMNAACHEBACE1 | |
| SCHEMBL23762310 | 0.78 | ENPP1 (1.00) | ENPP1AURKAACHEBACE1MAPK1 | |
| Hydrochloric Acid SCHEMBL30079921 | 0.77 | ENPP1 (0.98) | ENPP1AURKAACHEBACE1MAPK1 | |
| Hydrochloric Acid SCHEMBL23727134 | 0.77 | ENPP1 (0.98) | ENPP1AURKAACHEBACE1MAPK1 | |
| SCHEMBL15314918 | 0.77 | PRKDC (0.52) | ENPP1LMNAACHEBACE1MAPK1 | |
| SCHEMBL25656113 | 0.77 | PRKDC (0.52) | ENPP1LMNAACHEBACE1MAPK1 | |
| SCHEMBL23762321 | 0.77 | ENPP1 (0.81) | ENPP1AURKAACHEBACE1MAPK1 | |
| SCHEMBL15314919 | 0.75 | PRKDC (0.48) | ENPP1AURKALMNAACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | STINGRAY THERAPEUTICS INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | ENPP1, ENPP3, PPA1 | ENPP1 1/4885AURKA 3497/4885LMNA 3401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.