Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 9/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25656171 | 0.91 | ENPP1 (0.59) | ENPP1LRRK2ALDH1A1KDM4EKMT2A | |
| SCHEMBL25656176 | 0.89 | ENPP1 (0.58) | ENPP1LRRK2ALDH1A1KDM4EKMT2A | |
| SCHEMBL25656173 | 0.85 | ENPP1 (0.80) | ENPP1LRRK2ALDH1A1KDM4EKMT2A | |
| SCHEMBL25656018 | 0.84 | ENPP1 (0.59) | ENPP1LRRK2ALDH1A1KDM4EKMT2A | |
| SCHEMBL25656178 | 0.84 | ENPP1 (0.68) | ENPP1LRRK2ALDH1A1KDM4ECHRM4 | |
| SCHEMBL25656175 | 0.82 | ENPP1 (0.53) | ENPP1LRRK2ALDH1A1KDM4EKMT2A | |
| SCHEMBL25656104 | 0.81 | LRRK2 (0.57) | ENPP1LRRK2ALDH1A1KDM4ECHRM4 | |
| SCHEMBL23762323 | 0.79 | ENPP1 (0.77) | ENPP1SMN1; SMN2MAPT | |
| SCHEMBL25656101 | 0.78 | LRRK2 (0.53) | ENPP1LRRK2ALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30080072 | 0.78 | ENPP1 (0.75) | ENPP1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | STINGRAY THERAPEUTICS INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | ENPP1, ENPP3, PPA1 | ENPP1 1/4885LRRK2 3715/4885ALDH1A1 2287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.