Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 10/20 | 0.76 |
| ▸ | KIT | P10721 | 5/20 | 0.40 |
| ▸ | TDO2 | P48775 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23762391 | 0.87 | ENPP1 (1.00) | ENPP1KIT | |
| Hydrochloric Acid SCHEMBL23726792 | 0.86 | ENPP1 (0.98) | ENPP1KIT | |
| Hydrochloric Acid SCHEMBL30117275 | 0.86 | ENPP1 (0.98) | ENPP1KIT | |
| SCHEMBL25656211 | 0.84 | ENPP1 (0.54) | ENPP1KITCYP1A2CYP2D6CLK4 | |
| SCHEMBL25656205 | 0.81 | ENPP1 (0.75) | ENPP1KIT | |
| SCHEMBL25656210 | 0.80 | ENPP1 (0.54) | ENPP1KITTDO2USP2ALDH1A1 | |
| SCHEMBL23726281 | 0.75 | ENPP1 (0.75) | ENPP1KIT | |
| SCHEMBL23727079 | 0.74 | ENPP1 (0.77) | ENPP1KIT | |
| SCHEMBL25655992 | 0.72 | ENPP1 (0.51) | ENPP1KIT | |
| SCHEMBL23762250 | 0.71 | ENPP1 (0.81) | ENPP1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | STINGRAY THERAPEUTICS INC (US) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183212-A1 | INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF | ENPP1, ENPP3, PPA1 | ENPP1 1/4885KIT 4739/4885TDO2 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.