Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 19/20 | 0.44 |
| ▸ | CTSD | P07339 | 7/20 | 0.44 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL428039 | 0.80 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL430555 | 0.69 | BACE1 (0.61) | BACE1CTSDBACE2 | |
| SCHEMBL12592014 | 0.66 | BACE1 (0.63) | BACE1CTSD | |
| SCHEMBL427886 | 0.61 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL2570745 | 0.61 | BACE1 (0.42) | BACE1CTSD | |
| SCHEMBL428008 | 0.60 | BACE1 (0.73) | BACE1CTSD | |
| SCHEMBL428996 | 0.59 | BACE1 (0.67) | BACE1CTSD | |
| SCHEMBL12592723 | 0.59 | BACE1 (0.65) | BACE1CTSD | |
| SCHEMBL429122 | 0.58 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL430523 | 0.58 | BACE1 (0.78) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123674-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-06 | — | — | WO | disclosed |