Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 18/20 | 0.42 |
| ▸ | CTSD | P07339 | 5/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710745 | 0.82 | BACE1 (0.59) | BACE1CTSD | |
| SCHEMBL7713944 | 0.74 | BACE1 (0.62) | BACE1CTSD | |
| SCHEMBL7711171 | 0.74 | BACE1 (0.55) | BACE1CTSD | |
| SCHEMBL7711751 | 0.72 | BACE1 (0.52) | BACE1CTSD | |
| SCHEMBL2573113 | 0.71 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL7708619 | 0.71 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL7707977 | 0.70 | BACE1 (0.52) | BACE1CTSD | |
| SCHEMBL2577973 | 0.70 | BACE1 (0.48) | BACE1CTSD | |
| SCHEMBL2576404 | 0.69 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL2574316 | 0.68 | BACE1 (0.60) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |