Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.39 |
| ▸ | FABP7 | O15540 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29855327 | 0.84 | CASP3 (0.47) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL25179588 | 0.84 | CASP3 (0.47) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL25112440 | 0.82 | KMT2A (0.40) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL21837819 | 0.82 | CASR (0.38) | KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL29521277 | 0.81 | KMT2A (0.41) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL401458 | 0.81 | KMT2A (0.42) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL16060098 | 0.81 | KMT2A (0.41) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL23517944 | 0.81 | KMT2A (0.45) | KMT2AFABP5FABP7CASP3EPHX2 | |
| SCHEMBL31493935 | 0.81 | KMT2A (0.39) | KMT2AFABP5FABP7EPHX2 | |
| SCHEMBL15083572 | 0.81 | KMT2A (0.39) | KMT2AFABP5FABP7CASP3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | disclosed |
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | KRAS, NRAS, HRAS | KMT2A 3145/4885FABP5 4094/4885FABP7 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.