Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.45 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4343601 | 0.85 | KCNH2 (0.64) | MAPTTDP1L3MBTL1MEN1NPC1 | |
| SCHEMBL4343598 | 0.85 | KCNH2 (0.64) | MAPTTDP1L3MBTL1MEN1NPC1 | |
| SCHEMBL29186037 | 0.85 | KCNH2 (0.44) | MAPTTDP1L3MBTL1MEN1NPC1 | |
| SCHEMBL25658306 | 0.77 | KCNH2 (0.72) | MAPTTDP1L3MBTL1MEN1NPC1 | |
| SCHEMBL28208036 | 0.72 | KMT2A (0.49) | MAPTTDP1L3MBTL1MEN1NPC1 | |
| SCHEMBL20275930 | 0.72 | KCNH2 (0.65) | MAPTTDP1L3MBTL1MEN1NPC1 | |
| SCHEMBL11508824 | 0.72 | NPC1 (0.62) | MAPTTDP1L3MBTL1MEN1NPC1 | |
| SCHEMBL29397508 | 0.71 | KCNH2 (0.47) | MAPTTDP1MEN1NPC1MAPK1 | |
| SCHEMBL272969 | 0.71 | KCNH2 (0.47) | MAPTTDP1MEN1NPC1MAPK1 | |
| SCHEMBL272970 | 0.71 | KCNH2 (0.47) | MAPTTDP1MEN1NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648239-B2 | Azophenols as ERG oncogene inhibitors | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11648239-B2 | Azophenols as ERG oncogene inhibitors | ERG, ESR1, CBX2 | MAPT 4076/4885TDP1 1136/4885L3MBTL1 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.