Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 14/20 | 0.72 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5981718 | 0.84 | KCNH2 (1.00) | KCNH2RIOK2MAOAMAOBMAPT | |
| SCHEMBL30374239 | 0.84 | KCNH2 (1.00) | KCNH2RIOK2MAOAMAOBMAPT | |
| SCHEMBL5981715 | 0.84 | KCNH2 (1.00) | KCNH2RIOK2MAOAMAOBMAPT | |
| SCHEMBL31621739 | 0.84 | KCNH2 (1.00) | KCNH2RIOK2MAOAMAOBMAPT | |
| SCHEMBL25658305 | 0.79 | KCNH2 (0.56) | KCNH2RIOK2MAOAMAOBMAPT | |
| SCHEMBL25658307 | 0.77 | MAPT (0.47) | KCNH2RIOK2MAOAMAOBMAPT | |
| SCHEMBL20280313 | 0.77 | KCNH2 (0.65) | KCNH2RIOK2MAOAMAOBMAPT | |
| SCHEMBL1131920 | 0.76 | MAOA (1.00) | KCNH2RIOK2MAOAMAOBKMT2A | |
| SCHEMBL407009 | 0.76 | MAOA (1.00) | KCNH2RIOK2MAOAMAOBKMT2A | |
| SCHEMBL29351256 | 0.76 | MAOA (1.00) | KCNH2RIOK2MAOAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648239-B2 | Azophenols as ERG oncogene inhibitors | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (US) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11648239-B2 | Azophenols as ERG oncogene inhibitors | ERG, ESR1, CBX2 | KCNH2 3350/4885RIOK2 2127/4885MAOA 4156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.