SCHEMBL25659059

SCHEMBL25659059

N#Cc1cc(-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)c(-c2ccc(C#N)cc2C(F)(F)F)c(-n2c3ccc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)cc3c3cc(-c4ccc(C(F)(F)F)cc4C(F)(F)F)ccc32)c1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.38
ALOX5AP P20292 2/20 0.36
FEN1 P39748 2/20 0.36
CYP2C9 P11712 1/20 0.34
SCN9A Q15858 1/20 0.34
AR P10275 5/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
DGAT1 O75907 1/20 0.33
SOAT1 P35610 1/20 0.33
KCNH2 Q12809 1/20 0.33
TRPV4 Q9HBA0 1/20 0.33
ELANE P08246 2/20 0.32
NSD2 O96028 1/20 0.32
RXRA P19793 1/20 0.31
RXRG P48443 1/20 0.31
MAT2A P31153 1/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21258763 0.97 ALOX5AP (0.38) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL25659049 0.95 KIF11 (0.34) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL20925081 0.93 ALOX5AP (0.38) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL20111891 0.93 KIF11 (0.45) KIF11ALOX5APFEN1ARPTGDR2
SCHEMBL21258725 0.92 KIF11 (0.36) KIF11ARPTGDR2DGAT1SOAT1
SCHEMBL20112043 0.92 AR (0.36) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL20112038 0.92 AR (0.37) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL25659053 0.92 KIF11 (0.38) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL22985690 0.91 KIF11 (0.40) KIF11ALOX5APFEN1CYP2C9SCN9A
SCHEMBL21414156 0.90 ALOX5AP (0.36) KIF11ALOX5APFEN1CYP2C9SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
EP-3585777-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11825743-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 KIF11 3288/4885ALOX5AP 3126/4885FEN1 1566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.