Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25659783 | 0.90 | KLKB1 (0.52) | KLKB1 | |
| SCHEMBL24863510 | 0.89 | KLKB1 (0.38) | KLKB1 | |
| SCHEMBL24863408 | 0.88 | KLKB1 (0.57) | KLKB1 | |
| SCHEMBL25660016 | 0.87 | KLKB1 (0.41) | KLKB1 | |
| SCHEMBL24863781 | 0.81 | KLKB1 (0.65) | KLKB1 | |
| SCHEMBL25659770 | 0.80 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL25659991 | 0.80 | KLKB1 (0.49) | KLKB1 | |
| SCHEMBL25659981 | 0.80 | KLKB1 (0.61) | KLKB1 | |
| SCHEMBL25659839 | 0.80 | KLKB1 (0.58) | KLKB1 | |
| SCHEMBL25660357 | 0.79 | KLKB1 (0.42) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814371-B2 | Heterocyclic compound | MEDSHINE DISCOVERY INC. (CN) | 2023-11-14 | — | — | US | disclosed |
| US-20230167098-A1 | HETEROCYCLIC COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167098-A1 | HETEROCYCLIC COMPOUND | CYP11B2, CYP4F11, CYP11B1 | KLKB1 1724/4885 |
| US-11814371-B2 | Heterocyclic compound | CYP11B2, CYP4F11, CYP11B1 | KLKB1 1724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.