SCHEMBL25660253

SCHEMBL25660253

N#Cc1cc(C(F)(F)F)ccc1-c1cc(-n2c3cc(-n4c5ccccc5c5ccccc54)ccc3c3ccc(-n4c5ccccc5c5ccccc54)cc32)c(C#N)c(-n2c3cc(-n4c5ccccc5c5ccccc54)ccc3c3ccc(-n4c5ccccc5c5ccccc54)cc32)c1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.38
ALOX5AP P20292 1/20 0.37
FEN1 P39748 1/20 0.37
AR P10275 5/20 0.34
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SCN9A Q15858 4/20 0.32
MAT2A P31153 1/20 0.31
PTPN5 P54829 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26777536 1.00 KIF11 (0.38) KIF11ALOX5APFEN1ARPPARG
SCHEMBL25660316 0.95 KIF11 (0.43) KIF11ALOX5APFEN1ARALDH1A1
SCHEMBL25660252 0.94 ALOX5AP (0.37) KIF11ALOX5APFEN1ARPPARG
SCHEMBL26777532 0.94 ALOX5AP (0.37) KIF11ALOX5APFEN1ARPPARG
SCHEMBL25658541 0.94 ALOX5AP (0.41) KIF11ALOX5APFEN1ARALDH1A1
SCHEMBL25660317 0.90 ALOX5AP (0.39) KIF11ALOX5APFEN1ARALDH1A1
SCHEMBL26777534 0.90 ALOX5AP (0.38) KIF11ALOX5APFEN1ARALDH1A1
SCHEMBL25660237 0.90 KIF11 (0.42) KIF11ALOX5APFEN1ARPPARG
SCHEMBL25660124 0.90 KIF11 (0.39) KIF11ALOX5APFEN1ARALDH1A1
SCHEMBL21258795 0.90 KIF11 (0.38) KIF11ALOX5APFEN1ARPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
EP-3585777-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11825743-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 KIF11 3288/4885ALOX5AP 3126/4885FEN1 1566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.