Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 13/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 9/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 4/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 4/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25661100 | 1.00 | GRIK1 (0.50) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL13559485 | 0.87 | SLC1A2 (0.53) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL27690203 | 0.87 | SLC1A2 (0.53) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL14420351 | 0.85 | GRIK1 (0.55) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL899878 | 0.85 | GRIK1 (0.55) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL23581967 | 0.84 | GRIK1 (0.56) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL15649706 | 0.84 | GRIK1 (0.56) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL17204170 | 0.84 | GRIK1 (0.56) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL5936931 | 0.84 | GRIK1 (0.56) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL17204435 | 0.84 | GRIK1 (0.56) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158179-A1 | RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF | PAICS, LNPEP, DNPEP | GRIK1 2914/4885GRIK2 3197/4885SLC1A2 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.