Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20236440 | 0.77 | ALDH1A1 (0.47) | MAPTL3MBTL1KDM4EHPGDHCAR3 | |
| SCHEMBL27823817 | 0.77 | MAPT (0.41) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL27832731 | 0.77 | MAPT (0.41) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL12361793 | 0.76 | CYP2C9 (0.47) | MAPTSMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL17682295 | 0.76 | MAPT (0.42) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL2693391 | 0.75 | MAPT (0.39) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL4594866 | 0.74 | MAPK1 (0.50) | MAPTL3MBTL1KDM4ETDP1RAB9A | |
| SCHEMBL25659377 | 0.74 | KDM4E (0.36) | KDM4EHCAR3 | |
| SCHEMBL27717025 | 0.72 | BAZ2B (0.42) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 | |
| SCHEMBL567789 | 0.71 | MAPT (0.44) | MAPTSMN1; SMN2L3MBTL1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081232-A1 | DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME | ADCENTRX THERAPEUTICS INC. (US) | 2023-05-11 | — | — | WO | disclosed |