SCHEMBL25660933

SCHEMBL25660933

N#Cc1cccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)c(-c3ccc(C(F)(F)F)cc3C#N)cc2-n2c3ccccc3c3cc(-c4cccc(C#N)c4)ccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 1/20 0.40
PDK2 Q15119 1/20 0.39
MAT2A P31153 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.36
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
ENPP1 P22413 1/20 0.35
TRPA1 O75762 1/20 0.35
CETP P11597 1/20 0.35
GRIN1 Q05586 3/20 0.34
GRIN2B Q13224 3/20 0.34
XDH P47989 1/20 0.34
CCR6 P51684 1/20 0.33
KIF11 P52732 1/20 0.33
SGK1 O00141 1/20 0.33
PRF1 P14222 1/20 0.33
CHEK1 O14757 1/20 0.33
ALPL P05186 1/20 0.33
ALPI P09923 1/20 0.33
ALDH1A3 P47895 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25659718 0.96 PTPN5 (0.40) PTPN5PDK2MAT2APTGDR2ALOX5AP
SCHEMBL25660931 0.96 PTPN5 (0.41) PTPN5PDK2MAT2APTGDR2ALOX5AP
SCHEMBL21258817 0.94 PTPN5 (0.39) PTPN5PDK2MAT2APTGDR2ALOX5AP
SCHEMBL25659722 0.93 PTPN5 (0.40) PTPN5PDK2MAT2APTGDR2ALOX5AP
SCHEMBL25660930 0.92 KIF11 (0.41) PTPN5PDK2PTGDR2ALOX5APFEN1
SCHEMBL25659720 0.91 PTPN5 (0.40) PTPN5PDK2MAT2APTGDR2ALOX5AP
SCHEMBL21546604 0.90 PTGDR2 (0.40) PTPN5PDK2MAT2APTGDR2ALOX5AP
SCHEMBL26777703 0.90 KIF11 (0.37) PDK2MAT2AALOX5APFEN1TRPA1
SCHEMBL22761114 0.90 AR (0.37) PTPN5PDK2MAT2APTGDR2ALOX5AP
SCHEMBL25659963 0.90 PTPN5 (0.40) PTPN5PDK2MAT2APTGDR2ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11825743-B2 Organic molecules for use in organic optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
EP-3585777-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11825743-B2 Organic molecules for use in organic optoelectronic devices OR10J3, OR51E2, OCIAD2 PTPN5 4577/4885PDK2 1721/4885MAT2A 1252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.