Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.57 |
| ▸ | SRC | P12931 | 5/20 | 0.57 |
| ▸ | EGFR | P00533 | 13/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.55 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25663360 | 0.90 | KDR (0.54) | KDRSRCEGFREPHA2EPHB4 | |
| SCHEMBL25663372 | 0.88 | EGFR (0.59) | KDRSRCEGFRERBB2FGFR1 | |
| SCHEMBL30549061 | 0.86 | EGFR (0.73) | KDRSRCEGFREPHB4ERBB2 | |
| SCHEMBL25262108 | 0.86 | EGFR (0.73) | KDRSRCEGFREPHB4ERBB2 | |
| SCHEMBL26058979 | 0.86 | EGFR (0.67) | KDRSRCEGFREPHB4ERBB2 | |
| SCHEMBL25211674 | 0.83 | EGFR (0.79) | KDRSRCEGFREPHB4ERBB2 | |
| SCHEMBL30549063 | 0.83 | EGFR (0.79) | KDRSRCEGFREPHB4ERBB2 | |
| SCHEMBL25663071 | 0.80 | EGFR (0.55) | KDRSRCEGFREPHA2EPHB4 | |
| SCHEMBL26057658 | 0.78 | EGFR (0.66) | KDREGFRERBB2 | |
| SCHEMBL25663172 | 0.78 | SRC (0.60) | KDRSRCEGFREPHB4ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194443-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |