Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | NT5E | P21589 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552941 | 0.74 | CA2 (0.42) | TSHRSMN1; SMN2LCKFYNLMNA | |
| SCHEMBL11451068 | 0.70 | LCK (0.47) | TSHRSMN1; SMN2LCKFYNLMNA | |
| SCHEMBL11438990 | 0.68 | LCK (0.36) | TSHRSMN1; SMN2LCKFYNLMNA | |
| SCHEMBL646278 | 0.65 | LCK (0.46) | SNCATSHRSMN1; SMN2LCKFYN | |
| SCHEMBL8162990 | 0.65 | LCK (0.46) | SNCATSHRSMN1; SMN2LCKFYN | |
| SCHEMBL219222 | 0.65 | LCK (0.57) | TSHRSMN1; SMN2LCKFYNLMNA | |
| SCHEMBL10840928 | 0.64 | LCK (0.44) | SNCATSHRSMN1; SMN2LCKFYN | |
| Iodide SCHEMBL27949565 | 0.64 | LCK (0.44) | SNCATSHRSMN1; SMN2LCKFYN | |
| SCHEMBL84322 | 0.64 | LCK (0.44) | SNCATSHRSMN1; SMN2LCKFYN | |
| Hydrochloric Acid SCHEMBL27856239 | 0.64 | LCK (0.44) | SNCATSHRSMN1; SMN2LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382190-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | European Molecular Biology Laboratory (EMBL) (DE) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010085968-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS HIF-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010076034-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-07-08 | — | — | WO | disclosed |